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SHIC/FFAR Collaboration Seeks Japanese Encephalitis Virus Research Proposals

The Swine Health Information Center and the Foundation for Food & Agriculture Research (FFAR) have partnered to fund a $1 million research program to enhance US prevention, preparedness, and response capabilities for Japanese encephalitis virus, a transboundary disease risk for US introduction.

SHIC’s strategic mission to identify risks to swine health includes global and domestic disease monitoring to maintain an acute awareness of emerging swine diseases around the world. Japanese encephalitis is an emerging zoonotic disease identified through global monitoring as a priority for North American prevention and preparedness activities. JEV is transmitted through the bite of infected Culex mosquitoes and biosecurity practices focused on mosquito control are key to reducing risk. The US is currently negative for this mosquito-borne virus which has waterbirds as a natural reservoir but is capable of infecting pigs, humans, and horses.

In 2022, an outbreak of JEV genotype IV spread rapidly across new geographic regions of Australia affecting breeding swine herds and causing reproductive failure, delayed farrowing, stillbirths, mummified fetuses, abortions, and weak piglets. This recent incursion of a new JEV genotype into areas previously free from disease warrants the need for a close investigation of this virus and its potential for incursion and establishment in the US. Understanding the potential impacts of JEV on pork production in the US is critical to protecting the health of the US swine herd as well as mitigating the risk of this emerging disease.

In response to this emerging disease, SHIC and FFAR have partnered to invite proposal submissions from qualified researchers for funding consideration to address identified research priorities for JEV, including topic areas of 1) transmission and epidemiology, 2) mosquito control, 3) diagnostics, 4) communication, 5) surveillance, 6) compatible cases, 7) challenge models, 8) vaccines, 9) cross-protection, 10) competent vectors, 11) role of wildlife, 12) novel hosts, and 13) viral sequencing. Proposal information and a detailed list of research priorities can be found here.

Proposals should clearly state which of the identified SHIC/FFAR JEV research priorities will be addressed through the project. Collaborative projects that include the pork industry, international organizations, allied industry, academic institutions, and/or public/private partnerships are highly encouraged. Projects demonstrating the most urgent, timely completion, providing the greatest value to pork producers, and showing efficient use of funds will be prioritized for funding. Projects are requested to be completed within a 12-to-18-month period with sufficient justification required for extended project duration. The JEV research proposal template can be found here.

Total funding available for the SHIC/FFAR JEV Research Priorities is $1 million. Individual awards are capped at $250,000 but proposals may exceed the cap if sufficient justification is provided. Matching funds are encouraged but not required; the $250,000 cap applies to only those funds requested from SHIC/FFAR. All projects should strive to be unique, have a high impact, show value to pork producers, and have industry-wide benefit.

The deadline for proposal submission is 5:00 pm CDT on April 15, 2024. SHIC and FFAR are co-hosting an informational webinar on February 22, 2024, at 3:00 pm CST to provide additional details about the application criteria. Attendees must register to attend the webinar here. Additional information can be found at www.swinehealth.org. For questions, please contact Dr. Megan Niederwerder at mniederwerder@swinehealth.org or (785)452-8270 or Dr. Lisa Becton at lbecton@swinehealth.org or (515)724-9491.

The Foundation for Food & Agriculture Research (FFAR) is a non-profit organization established in the 2014 Farm Bill to build public-private partnerships that fund bold research addressing food and agriculture challenges. SHIC and FFAR collaborated with the Pork Checkoff to fund the Wean-to-Harvest Biosecurity Program research project now underway.

The Swine Health Information Center, launched in 2015 with Pork Checkoff funding, protects and enhances the health of the US swine herd by minimizing the impact of emerging disease threats through preparedness, coordinated communications, global disease monitoring, analysis of swine health data, and targeted research investments. As a conduit of information and research, SHIC encourages sharing of its publications and research. Forward, reprint, and quote SHIC material freely. For more information, visit http://www.swinehealth.org or contact Dr. Megan Niederwerder at mniederwerder@swinehealth.org or Dr. Lisa Becton at lbecton@swinehealth.org.