The Swine Health Information Center’s (SHIC) September Domestic Swine Disease Monitoring Report is available. This month’s Domestic Swine Disease Monitoring Report shows a similar overall case positivity for porcine reproductive and respiratory syndrome virus (PRRSV), porcine epidemic diarrhea virus (PEDV), and porcine deltacoronavirus (PDCoV) cases in August compared to July. Detection for these agents was within expected parameters for this time of the year. Overall, Mycoplasma hyopneumoniae is following an expected trend of increased detection. At the state level, detection of PRRSV was three standard deviations above expected in Missouri (MO). In the podcast, the SDRS hosts talk with Dr. Derald Holtkamp about strategies to keep disease activity low. They also discuss the economics of disease management and the value of year around biosecurity practices.