TY - JOUR AU - Herrman, TJ AU - Behnke, KC AU - Loughin, TM TI - Mixing and clean-out properties of sulfamethazine and carbadox in swine feed T2 - Journal of Swine Health and Production JF - Journal of Swine Health and Production J2 - JSHAP SN - 1537-209X DP - American Association of Swine Veterinarians PB - American Association of Swine Veterinarians DA - 1995/Sep// PY - 1995 VL - 3 M1 - 5 IS - 5 M2 - 195 SP - 195-198 UR - https://www.aasv.org/shap/abstracts/abstract.php?v3n5p195 L1 - https://www.aasv.org/shap/issues/v3n5/v3n5p195.pdf KW - swine KW - feed KW - sulfamethazine KW - carbadox N2 - Two forms of sulfamethazine (pelleted and granular) and one form of carbadox (granular) were evaluated for their mixing and clean-out properties in replicated batches of swine feed prepared at the research feed mill at Kansas State University. Analysis of variance indicated that carbadox was incorporated into the feed more uniformly than sulfamethazine. Additional mixing beyond 1.5 minutes did not improve drug distribution (P>0.05). A paired-comparison T-test was used to compare mixing properties of drugs versus salt (the latter is commonly used to test mixer performance). We found the mixing properties of sulfamethazine and salt to be different (P <0.05), whereas those of carbadox and salt did not differ (P >0.05). Ground corn was used to flush the mixer and conveying system between feed batches; then the mixer, leg, and sack-off bin were cleaned, and materials were assayed for drug carryover. Sulfamethazine was detected in the mixer cleanout material at concentrations of 12.6 ppm and 8.1 ppm for the granular and pellet forms, respectively. Carbadox carryover was not detected in mixer clean-out material. Detestable concentrations for all three drugs occurred in cleanout material from the leg and sack-off bin. ER -